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Accelerated aging of the brain transcriptome by the common chemotherapeutic doxorubicin

Cancer is one of the most common age-related diseases, and over one-third of cancer patients will receive chemotherapy. One frequently reported side effect of chemotherapeutic agents like doxorubicin (Doxo) is impaired cognitive function, commonly known as “chemotherapy-induced cognitive impairment...

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Publicat a:Exp Gerontol
Autors principals: Cavalier, Alyssa N., Clayton, Zachary S., Hutton, David A., Wahl, Devin, Reisz, Julie A., Melov, Simon, Campisi, Judith, Seals, Douglas R., LaRocca, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319121/
https://ncbi.nlm.nih.gov/pubmed/34147619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2021.111451
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