Ubiquitin‐proteasome‐system and enzymes of energy metabolism in skeletal muscle of patients with HFpEF and HFrEF

BACKGROUND: Skeletal muscle (SM) alterations contribute to exercise intolerance in heart failure patients with preserved (HFpEF) or reduced (HFrEF) left ventricular ejection fraction (LVEF). Protein degradation via the ubiquitin‐proteasome‐system (UPS), nuclear apoptosis, and reduced mitochondrial e...

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Bibliografiske detaljer
Udgivet i:ESC Heart Fail
Main Authors: Adams, Volker, Wunderlich, Sebastian, Mangner, Norman, Hommel, Jennifer, Esefeld, Katrin, Gielen, Stephan, Halle, Martin, Ellingsen, Øyvind, Van Craenenbroeck, Emeline M., Wisløff, Ulrik, Pieske, Burkert, Linke, Axel, Winzer, Ephraim B.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Original Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318515/
https://ncbi.nlm.nih.gov/pubmed/33955206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ehf2.13405
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