Ubiquitin‐proteasome‐system and enzymes of energy metabolism in skeletal muscle of patients with HFpEF and HFrEF

BACKGROUND: Skeletal muscle (SM) alterations contribute to exercise intolerance in heart failure patients with preserved (HFpEF) or reduced (HFrEF) left ventricular ejection fraction (LVEF). Protein degradation via the ubiquitin‐proteasome‐system (UPS), nuclear apoptosis, and reduced mitochondrial e...

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Dades bibliogràfiques
Publicat a:ESC Heart Fail
Autors principals: Adams, Volker, Wunderlich, Sebastian, Mangner, Norman, Hommel, Jennifer, Esefeld, Katrin, Gielen, Stephan, Halle, Martin, Ellingsen, Øyvind, Van Craenenbroeck, Emeline M., Wisløff, Ulrik, Pieske, Burkert, Linke, Axel, Winzer, Ephraim B.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Original Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318515/
https://ncbi.nlm.nih.gov/pubmed/33955206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ehf2.13405
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