Ubiquitin‐proteasome‐system and enzymes of energy metabolism in skeletal muscle of patients with HFpEF and HFrEF

BACKGROUND: Skeletal muscle (SM) alterations contribute to exercise intolerance in heart failure patients with preserved (HFpEF) or reduced (HFrEF) left ventricular ejection fraction (LVEF). Protein degradation via the ubiquitin‐proteasome‐system (UPS), nuclear apoptosis, and reduced mitochondrial e...

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Dettagli Bibliografici
Pubblicato in:ESC Heart Fail
Autori principali: Adams, Volker, Wunderlich, Sebastian, Mangner, Norman, Hommel, Jennifer, Esefeld, Katrin, Gielen, Stephan, Halle, Martin, Ellingsen, Øyvind, Van Craenenbroeck, Emeline M., Wisløff, Ulrik, Pieske, Burkert, Linke, Axel, Winzer, Ephraim B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
Soggetti:
Original Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318515/
https://ncbi.nlm.nih.gov/pubmed/33955206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ehf2.13405
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