Estetrol Cotreatment of Androgen Deprivation Therapy in Infiltrating or Metastatic, Castration-sensitive Prostate Cancer: A Randomized, Double-blind, Phase II Trial (PCombi)

BACKGROUND: Androgen deprivation therapy (ADT) for prostate cancer with luteinizing hormone-releasing hormone (LHRH) agonists can be improved. OBJECTIVE: To assess safety, the frequency and severity of hot flushes (HFs), bone health, and antitumor effects of high-dose estetrol (HDE4) when combined w...

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Detalhes bibliográficos
Publicado no:Eur Urol Open Sci
Main Authors: Coelingh Bennink, Herjan J.T., van Moorselaar, Jeroen A., Crawford, E. David, Roos, Erik P.M., Somford, Diederik M., Roeleveld, Ton A., de Haan, Tjard D., van Melick, Harm H.E., Reisman, Yacov, Zimmerman, Yvette, van Osta, Gonnie, Krijgh, Jan, Shore, Neal D., Saad, Fred, Schally, Andrew V., Debruyne, Frans M.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Prostate Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317802/
https://ncbi.nlm.nih.gov/pubmed/34337526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euros.2021.04.005
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