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Tumor suppression, dose-limiting toxicity and wellbeing with the fetal estrogen estetrol in patients with advanced breast cancer

PURPOSE: The aim of this study (the ABCE4 study) was to assess dose-limiting toxicity (DLT), safety, tolerability and preliminary efficacy of high doses of the fetal estrogen estetrol (E4) in postmenopausal patients with heavily pretreated, locally advanced and/or metastatic ER+/HER2−breast cancer,...

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Publicat a:J Cancer Res Clin Oncol
Autors principals: Schmidt, Marcus, Lenhard, Hans, Hoenig, Arnd, Zimmerman, Yvette, Krijgh, Jan, Jansen, Monique, Coelingh Bennink, Herjan J. T.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076125/
https://ncbi.nlm.nih.gov/pubmed/33242131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-020-03472-8
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