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A distinct assembly pathway of the human 39S late pre-mitoribosome

Assembly of the mitoribosome is largely enigmatic and involves numerous assembly factors. Little is known about their function and the architectural transitions of the pre-ribosomal intermediates. Here, we solve cryo-EM structures of the human 39S large subunit pre-ribosomes, representing five disti...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Cheng, Jingdong, Berninghausen, Otto, Beckmann, Roland
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316566/
https://ncbi.nlm.nih.gov/pubmed/34315873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24818-x
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