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A distinct assembly pathway of the human 39S late pre-mitoribosome

Assembly of the mitoribosome is largely enigmatic and involves numerous assembly factors. Little is known about their function and the architectural transitions of the pre-ribosomal intermediates. Here, we solve cryo-EM structures of the human 39S large subunit pre-ribosomes, representing five disti...

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Publicat a:Nat Commun
Autors principals: Cheng, Jingdong, Berninghausen, Otto, Beckmann, Roland
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316566/
https://ncbi.nlm.nih.gov/pubmed/34315873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24818-x
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