Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes

Eukaryotic 60S ribosomal subunits are comprised of three rRNAs and ∼50 ribosomal proteins. The initial steps of their formation take place in the nucleolus, but, owing to a lack of structural information, this process is poorly understood. Using cryo-EM, we solved structures of early 60S biogenesis...

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Udgivet i:Cell
Main Authors: Kater, Lukas, Thoms, Matthias, Barrio-Garcia, Clara, Cheng, Jingdong, Ismail, Sherif, Ahmed, Yasar Luqman, Bange, Gert, Kressler, Dieter, Berninghausen, Otto, Sinning, Irmgard, Hurt, Ed, Beckmann, Roland
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745149/
https://ncbi.nlm.nih.gov/pubmed/29245012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.11.039
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