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Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis
The NLRP3 inflammasome mediates the production of proinflammatory cytokines and initiates inflammatory cell death. Although NLRP3 is essential for innate immunity, aberrant NLRP3 inflammasome activation contributes to a wide variety of inflammatory diseases. Understanding the pathways that control N...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8316491/ https://ncbi.nlm.nih.gov/pubmed/34315884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24784-4 |
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