TRIB2 desensitizes ferroptosis via βTrCP-mediated TFRC ubiquitiantion in liver cancer cells

Tribbles homolog 2 (TRIB2) is known to boost liver tumorigenesis via regulating Ubiquitin (Ub) proteasome system (UPS). At least two ways are involved, i.e., acts as an adaptor protein to modulate ubiquitination functions of certain ubiquitin E3 ligases (E3s) and reduces global Ub levels via increas...

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Bibliografiset tiedot
Julkaisussa:Cell Death Discov
Päätekijät: Guo, Susu, Chen, Yuxin, Xue, Xiangfei, Yang, Yueyue, Wang, Yikun, Qiu, Shiyu, Cui, Jiangtao, Zhang, Xiao, Ma, Lifang, Qiao, Yongxia, Wang, Jiayi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316344/
https://ncbi.nlm.nih.gov/pubmed/34315867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00574-1
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