RRM2 protects against ferroptosis and is a tumor biomarker for liver cancer

BACKGROUND: Ferroptosis is the process of cell death triggered by lipid peroxides, and inhibition of glutathione (GSH) synthesis leads to ferroptosis. Liver cancer progression is closely linked to ferroptosis suppression. However, the mechanism by which inhibition of GSH synthesis suppresses potenti...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Yang, Yueyue, Lin, Jiafei, Guo, Susu, Xue, Xiangfei, Wang, Yikun, Qiu, Shiyu, Cui, Jiangtao, Ma, Lifang, Zhang, Xiao, Wang, Jiayi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720568/
https://ncbi.nlm.nih.gov/pubmed/33372599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01689-8
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