RRM2 protects against ferroptosis and is a tumor biomarker for liver cancer

BACKGROUND: Ferroptosis is the process of cell death triggered by lipid peroxides, and inhibition of glutathione (GSH) synthesis leads to ferroptosis. Liver cancer progression is closely linked to ferroptosis suppression. However, the mechanism by which inhibition of GSH synthesis suppresses potenti...

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Dettagli Bibliografici
Pubblicato in:Cancer Cell Int
Autori principali: Yang, Yueyue, Lin, Jiafei, Guo, Susu, Xue, Xiangfei, Wang, Yikun, Qiu, Shiyu, Cui, Jiangtao, Ma, Lifang, Zhang, Xiao, Wang, Jiayi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Primary Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720568/
https://ncbi.nlm.nih.gov/pubmed/33372599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01689-8
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