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Efficacy and Associated Drug Exposures of Isavuconazole and Fluconazole in an Experimental Model of Coccidioidomycosis

Coccidioides spp. are important pathogens in regions where they are endemic, and new treatment options are needed. Here, isavuconazonium sulfate (ISAVUSULF) and fluconazole (FLU) were evaluated in experimental disseminated coccidioidomycosis to characterize drug exposures associated with efficacy. B...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kovanda, Laura L., Sass, Gabriele, Martinez, Marife, Clemons, Karl V., Nazik, Hasan, Kitt, Therese M., Wiederhold, Nathan, Hope, William W., Stevens, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316117/
https://ncbi.nlm.nih.gov/pubmed/33782009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02344-20
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