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Impact of Mucositis on Absorption and Systemic Drug Exposure of Isavuconazole
Isavuconazonium sulfate is the water-soluble prodrug of isavuconazole. Population analyses have demonstrated relatively predictable pharmacokinetic (PK) behavior in diverse patient populations. We evaluated the impact of mucositis on the oral isavuconazole exposure using population PK modeling. This...
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Publicado no: | Antimicrob Agents Chemother |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5444187/ https://ncbi.nlm.nih.gov/pubmed/28289034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00101-17 |
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