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Efficacy and Associated Drug Exposures of Isavuconazole and Fluconazole in an Experimental Model of Coccidioidomycosis

Coccidioides spp. are important pathogens in regions where they are endemic, and new treatment options are needed. Here, isavuconazonium sulfate (ISAVUSULF) and fluconazole (FLU) were evaluated in experimental disseminated coccidioidomycosis to characterize drug exposures associated with efficacy. B...

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Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Kovanda, Laura L., Sass, Gabriele, Martinez, Marife, Clemons, Karl V., Nazik, Hasan, Kitt, Therese M., Wiederhold, Nathan, Hope, William W., Stevens, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316117/
https://ncbi.nlm.nih.gov/pubmed/33782009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02344-20
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