Discovery of a Novel Respiratory Syncytial Virus Replication Inhibitor

A high-throughput screen of a Roche internal chemical library based on inhibition of the respiratory syncytial virus (RSV)-induced cytopathic effect (CPE) on HEp-2 cells was performed to identify RSV inhibitors. Over 2,000 hits were identified and confirmed to be efficacious against RSV infection in...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Wang, Li, Zhu, Qihui, Xiang, Kunlun, Zhang, Yaling, Li, Baocun, Yu, Xin, Yang, Guang, Liang, Chungen, Yun, Hongying, Zhang, Meifang, Qin, Ning, Gao, Lu
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316115/
https://ncbi.nlm.nih.gov/pubmed/33782012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02576-20
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