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Deubiquitinating Enzyme USP21 Inhibits HIV-1 Replication by Downregulating Tat Expression
Ubiquitination plays an important role in human immunodeficiency virus 1 (HIV-1) infection. HIV proteins such as Vif and Vpx mediate the degradation of the host proteins APOBEC3 and SAMHD1, respectively, through the proteasome pathway. However, whether deubiquitylating enzymes play an essential role...
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| Pubblicato in: | J Virol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8316079/ https://ncbi.nlm.nih.gov/pubmed/33827943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00460-21 |
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