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Inhibition of Escherichia coli Lipoprotein Diacylglyceryl Transferase Is Insensitive to Resistance Caused by Deletion of Braun’s Lipoprotein

Lipoprotein diacylglyceryl transferase (Lgt) catalyzes the first step in the biogenesis of Gram-negative bacterial lipoproteins which play crucial roles in bacterial growth and pathogenesis. We demonstrate that Lgt depletion in a clinical uropathogenic Escherichia coli strain leads to permeabilizati...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Main Authors: Diao, Jingyu, Komura, Rie, Sano, Tatsuya, Pantua, Homer, Storek, Kelly M., Inaba, Hiroko, Ogawa, Haruhiko, Noland, Cameron L., Peng, Yutian, Gloor, Susan L., Yan, Donghong, Kang, Jing, Katakam, Anand Kumar, Volny, Michael, Liu, Peter, Nickerson, Nicholas N., Sandoval, Wendy, Austin, Cary D., Murray, Jeremy, Rutherford, Steven T., Reichelt, Mike, Xu, Yiming, Xu, Min, Yanagida, Hayato, Nishikawa, Junichi, Reid, Patrick C., Cunningham, Christian N., Kapadia, Sharookh B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316002/
https://ncbi.nlm.nih.gov/pubmed/33875545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00149-21
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