Inhibition of Escherichia coli Lipoprotein Diacylglyceryl Transferase Is Insensitive to Resistance Caused by Deletion of Braun’s Lipoprotein

Lipoprotein diacylglyceryl transferase (Lgt) catalyzes the first step in the biogenesis of Gram-negative bacterial lipoproteins which play crucial roles in bacterial growth and pathogenesis. We demonstrate that Lgt depletion in a clinical uropathogenic Escherichia coli strain leads to permeabilizati...

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Publicat a:J Bacteriol
Autors principals: Diao, Jingyu, Komura, Rie, Sano, Tatsuya, Pantua, Homer, Storek, Kelly M., Inaba, Hiroko, Ogawa, Haruhiko, Noland, Cameron L., Peng, Yutian, Gloor, Susan L., Yan, Donghong, Kang, Jing, Katakam, Anand Kumar, Volny, Michael, Liu, Peter, Nickerson, Nicholas N., Sandoval, Wendy, Austin, Cary D., Murray, Jeremy, Rutherford, Steven T., Reichelt, Mike, Xu, Yiming, Xu, Min, Yanagida, Hayato, Nishikawa, Junichi, Reid, Patrick C., Cunningham, Christian N., Kapadia, Sharookh B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316002/
https://ncbi.nlm.nih.gov/pubmed/33875545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00149-21
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