Novel Specific Metallo-β-Lactamase Inhibitor ANT2681 Restores Meropenem Activity to Clinically Effective Levels against NDM-Positive Enterobacterales

The global dissemination of metallo-β-lactamase (MBL)-producing carbapenem-resistant Enterobacterales (CRE) is a serious public health concern. Specifically, NDM (New Delhi MBL) has been a major cause of carbapenem therapy failures in recent years, particularly as effective treatments for serine-β-l...

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Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Zalacain, Magdalena, Lozano, Clarisse, Llanos, Agustina, Sprynski, Nicolas, Valmont, Thomas, De Piano, Cyntia, Davies, David, Leiris, Simon, Sable, Carole, Ledoux, Adeline, Morrissey, Ian, Lemonnier, Marc, Everett, Martin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315971/
https://ncbi.nlm.nih.gov/pubmed/33820763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00203-21
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