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Pyruvate Production by Escherichia coli by Use of Pyruvate Dehydrogenase Variants
Altering metabolic flux at a key branch point in metabolism has commonly been accomplished through gene knockouts or by modulating gene expression. An alternative approach to direct metabolic flux preferentially toward a product is decreasing the activity of a key enzyme through protein engineering....
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| Veröffentlicht in: | Appl Environ Microbiol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8315933/ https://ncbi.nlm.nih.gov/pubmed/33863707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00487-21 |
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