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Effects of Growth Mode and Pyruvate Carboxylase on Succinic Acid Production by Metabolically Engineered Strains of Escherichia coli

Escherichia coli NZN111, which lacks activities for pyruvate-formate lyase and lactate dehydrogenase, and AFP111, a derivative which contains an additional mutation in ptsG (a gene encoding an enzyme of the glucose phophotransferase system), accumulate significant levels of succinic acid (succinate)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vemuri, G. N., Eiteman, M. A., Altman, E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC123851/
https://ncbi.nlm.nih.gov/pubmed/11916689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.4.1715-1727.2002
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