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Pyruvate Production by Escherichia coli by Use of Pyruvate Dehydrogenase Variants

Altering metabolic flux at a key branch point in metabolism has commonly been accomplished through gene knockouts or by modulating gene expression. An alternative approach to direct metabolic flux preferentially toward a product is decreasing the activity of a key enzyme through protein engineering....

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書目詳細資料
發表在:Appl Environ Microbiol
Main Authors: Moxley, W. Chris, Eiteman, Mark A.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315933/
https://ncbi.nlm.nih.gov/pubmed/33863707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00487-21
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