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Establishing the allosteric mechanism in CRISPR-Cas9
Allostery is a fundamental property of proteins, which regulates biochemical information transfer between spatially distant sites. Here, we report on the critical role of molecular dynamics (MD) simulations in discovering the mechanism of allosteric communication within CRISPR-Cas9, a leading genome...
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| 出版年: | Wiley Interdiscip Rev Comput Mol Sci |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8315640/ https://ncbi.nlm.nih.gov/pubmed/34322166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wcms.1503 |
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