Llwytho...

Establishing the allosteric mechanism in CRISPR-Cas9

Allostery is a fundamental property of proteins, which regulates biochemical information transfer between spatially distant sites. Here, we report on the critical role of molecular dynamics (MD) simulations in discovering the mechanism of allosteric communication within CRISPR-Cas9, a leading genome...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Wiley Interdiscip Rev Comput Mol Sci
Prif Awduron: Nierzwicki, Łukasz, Arantes, Pablo Ricardo, Saha, Aakash, Palermo, Giulia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315640/
https://ncbi.nlm.nih.gov/pubmed/34322166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wcms.1503
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