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Pushing the limit on laminopathies
Mutations to lamins in skeletal muscle cells have been shown to reduce nuclear stability, increase nuclear envelope rupture, and induce DNA damage and cell death. New research shows that limiting mechanical loads can rescue myofibre function and viability.
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| Publicado no: | Nat Mater |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8315305/ https://ncbi.nlm.nih.gov/pubmed/32210401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41563-020-0648-1 |
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