QRICH1 Dictates the Outcome of ER Stress through Transcriptional Control of Proteostasis

Perturbation of tissue homeostasis accompanies a diversity of inflammatory pathologies elicits endoplasmic reticulum (ER) stress, protein misfolding, and cell death. ER stress triggers initiation of the unfolded protein response (UPR), which determines divergent cell fate decisions, either promoting...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: You, Kwontae, Wang, Lingfei, Chou, Chih-Hung, Liu, Kai, Nakata, Toru, Jaiswal, Alok, Yao, Junmei, Lefkovith, Ariel, Omar, Abdifatah, Perrigoue, Jacqueline G., Towne, Jennifer E., Regev, Aviv, Graham, Daniel B., Xavier, Ramnik J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315080/
https://ncbi.nlm.nih.gov/pubmed/33384352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abb6896
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