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Gene Therapy Strategies to Restore ER Proteostasis in Disease
Proteostasis alterations are proposed as a transversal hallmark of several pathological conditions, including metabolic disorders, mechanical injury, cardiac malfunction, neurodegeneration, and cancer. Strategies to improve proteostasis aim to reduce the accumulation of specific disease-related misf...
Gespeichert in:
| Veröffentlicht in: | Mol Ther |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Gene & Cell Therapy
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5986993/ https://ncbi.nlm.nih.gov/pubmed/29728295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.04.004 |
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