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RESETing ER proteostasis: selective stress pathway hidden in the secretory route
The efficient folding of membrane and secreted proteins relies on the unfolded protein response (UPR) to buffer fluctuations in the load of misfolded proteins. Although the UPR is thought to operate on a generic manner to maintain ER proteostasis, a recent study revealed the existence of a novel mec...
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| Опубликовано в: : | EMBO J |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BlackWell Publishing Ltd
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4283403/ https://ncbi.nlm.nih.gov/pubmed/25190517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489845 |
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