Association of Clonal Hematopoiesis with Incident Heart Failure

BACKGROUND: Age-related clonal hematopoiesis of indeterminate potential (CHIP), defined as clonally expanded leukemogenic mutations (particularly in DNMT3A, TET2, ASXL1, JAK2) in asymptomatic individuals, is associated with cardiovascular events, including recurrent heart failure (HF). OBJECTIVES: W...

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Julkaisussa:J Am Coll Cardiol
Päätekijät: Yu, Bing, Roberts, Mary B., Raffield, Laura M., Zekavat, Seyedeh Maryam, Nguyen, Ngoc Quynh H., Biggs, Mary Lou, Brown, Michael R., Griffin, Gabriel, Desai, Pinkal, Correa, Adolfo, Morrison, Alanna C., Shah, Amil M., Niroula, Abhishek, Uddin, Md Mesbah, Honigberg, Michael C., Ebert, Benjamin L., Psaty, Bruce M., Whitsel, Eric A., Manson, JoAnn E., Kooperberg, Charles, Bick, Alexander G., Ballantyne, Christie M., Reiner, Alex P., Natarajan, Pradeep, Eaton, Charles B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2021
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313294/
https://ncbi.nlm.nih.gov/pubmed/34210413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2021.04.085
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