Association of Clonal Hematopoiesis with Incident Heart Failure

BACKGROUND: Age-related clonal hematopoiesis of indeterminate potential (CHIP), defined as clonally expanded leukemogenic mutations (particularly in DNMT3A, TET2, ASXL1, JAK2) in asymptomatic individuals, is associated with cardiovascular events, including recurrent heart failure (HF). OBJECTIVES: W...

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Detalhes bibliográficos
Publicado no:J Am Coll Cardiol
Main Authors: Yu, Bing, Roberts, Mary B., Raffield, Laura M., Zekavat, Seyedeh Maryam, Nguyen, Ngoc Quynh H., Biggs, Mary Lou, Brown, Michael R., Griffin, Gabriel, Desai, Pinkal, Correa, Adolfo, Morrison, Alanna C., Shah, Amil M., Niroula, Abhishek, Uddin, Md Mesbah, Honigberg, Michael C., Ebert, Benjamin L., Psaty, Bruce M., Whitsel, Eric A., Manson, JoAnn E., Kooperberg, Charles, Bick, Alexander G., Ballantyne, Christie M., Reiner, Alex P., Natarajan, Pradeep, Eaton, Charles B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313294/
https://ncbi.nlm.nih.gov/pubmed/34210413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2021.04.085
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