Association of Clonal Hematopoiesis with Incident Heart Failure

BACKGROUND: Age-related clonal hematopoiesis of indeterminate potential (CHIP), defined as clonally expanded leukemogenic mutations (particularly in DNMT3A, TET2, ASXL1, JAK2) in asymptomatic individuals, is associated with cardiovascular events, including recurrent heart failure (HF). OBJECTIVES: W...

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Vydáno v:J Am Coll Cardiol
Hlavní autoři: Yu, Bing, Roberts, Mary B., Raffield, Laura M., Zekavat, Seyedeh Maryam, Nguyen, Ngoc Quynh H., Biggs, Mary Lou, Brown, Michael R., Griffin, Gabriel, Desai, Pinkal, Correa, Adolfo, Morrison, Alanna C., Shah, Amil M., Niroula, Abhishek, Uddin, Md Mesbah, Honigberg, Michael C., Ebert, Benjamin L., Psaty, Bruce M., Whitsel, Eric A., Manson, JoAnn E., Kooperberg, Charles, Bick, Alexander G., Ballantyne, Christie M., Reiner, Alex P., Natarajan, Pradeep, Eaton, Charles B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313294/
https://ncbi.nlm.nih.gov/pubmed/34210413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2021.04.085
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