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Defining the Glycosaminoglycan Interactions of Complement Factor H–Related Protein 5

Complement activation is an important mediator of kidney injury in glomerulonephritis. Complement factor H (FH) and FH-related protein 5 (FHR-5) influence complement activation in C3 glomerulopathy and IgA nephropathy by differentially regulating glomerular complement. FH is a negative regulator of...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Gyapon-Quast, Frederick, Goicoechea de Jorge, Elena, Malik, Talat, Wu, Nian, Yu, Jin, Chai, Wengang, Feizi, Ten, Liu, Yan, Pickering, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado: AAI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313009/
https://ncbi.nlm.nih.gov/pubmed/34193601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000072
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