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Physiologically Based Pharmacokinetic Models Are Effective Support for Pediatric Drug Development
Pediatric drug development faces many difficulties. Traditionally, pediatric drug doses are simply calculated linearly based on the body weight, age, and body surface area of adults. Due to the ontogeny of children, this simple linear scaling may lead to drug overdose in pediatric patients. The phys...
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| Gepubliceerd in: | AAPS PharmSciTech |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Springer International Publishing
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8312709/ https://ncbi.nlm.nih.gov/pubmed/34312742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-021-02076-w |
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