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Physiologically Based Pharmacokinetic Models Are Effective Support for Pediatric Drug Development
Pediatric drug development faces many difficulties. Traditionally, pediatric drug doses are simply calculated linearly based on the body weight, age, and body surface area of adults. Due to the ontogeny of children, this simple linear scaling may lead to drug overdose in pediatric patients. The phys...
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| Publicado no: | AAPS PharmSciTech |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8312709/ https://ncbi.nlm.nih.gov/pubmed/34312742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-021-02076-w |
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