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NELL2-cdc42 signaling regulates BAF complexes and Ewing sarcoma cell growth
BAF chromatin remodeling complexes play important roles in chromatin regulation and cancer. Here, we report that Ewing sarcoma cells are dependent on the autocrine signaling mediated by NELL2, a secreted glycoprotein that has been characterized as an axon guidance molecule. NELL2 uses Robo3 as the r...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8312579/ https://ncbi.nlm.nih.gov/pubmed/34233189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109254 |
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