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GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth
We report here that the autocrine signaling mediated by growth and differentiation factor 6 (GDF6), a member of the bone morphogenetic protein (BMP) family of cytokines, maintains Ewing sarcoma growth by preventing Src hyperactivation. Surprisingly, Ewing sarcoma depends on the prodomain, not the BM...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7688343/ https://ncbi.nlm.nih.gov/pubmed/33147457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108332 |
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