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Chloroquine suppresses proliferation and invasion and induces apoptosis of osteosarcoma cells associated with inhibition of phosphorylation of STAT3

Background: Osteosarcoma (OS) is characterized by a high rate of metastasis. It has been found that tumor cells can bypass apoptosis which leads to an uncontrolled proliferation, but chloroquine (CQ) can have an effect on the tumors by inducing apoptosis. We aimed to explore the effects and the hypo...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Chen, Chenglong, Zhang, Hongliang, Yu, Yiyang, Huang, Qingshan, Wang, Wei, Niu, Jianfang, Lou, Jingbing, Ren, Tingting, Huang, Yi, Guo, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312460/
https://ncbi.nlm.nih.gov/pubmed/34170850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.203196
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