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Chloroquine suppresses proliferation and invasion and induces apoptosis of osteosarcoma cells associated with inhibition of phosphorylation of STAT3

Background: Osteosarcoma (OS) is characterized by a high rate of metastasis. It has been found that tumor cells can bypass apoptosis which leads to an uncontrolled proliferation, but chloroquine (CQ) can have an effect on the tumors by inducing apoptosis. We aimed to explore the effects and the hypo...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Chen, Chenglong, Zhang, Hongliang, Yu, Yiyang, Huang, Qingshan, Wang, Wei, Niu, Jianfang, Lou, Jingbing, Ren, Tingting, Huang, Yi, Guo, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312460/
https://ncbi.nlm.nih.gov/pubmed/34170850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.203196
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