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Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7

In pathogenic mycobacteria, transcriptional responses to antibiotics result in induced antibiotic-resistance. WhiB7 belongs to the Actinobacteria-specific family of Fe-S containing transcription factors and plays a crucial role in inducible antibiotic-resistance in mycobacteria. Here we present cryo...

詳細記述

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書誌詳細
出版年:Mol Cell
主要な著者: Lilic, Mirjana, Darst, Seth A., Campbell, Elizabeth A.
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8311663/
https://ncbi.nlm.nih.gov/pubmed/34171296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2021.05.017
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