Aminoglycoside Cross-Resistance in Mycobacterium tuberculosis Due to Mutations in the 5′ Untranslated Region of whiB7

Since the discovery of streptomycin's bactericidal activity against Mycobacterium tuberculosis, aminoglycosides have been utilized to treat tuberculosis (TB). Today, the aminoglycosides kanamycin and amikacin are used to treat multidrug-resistant (MDR) TB, and resistance to any of the second-li...

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Detalhes bibliográficos
Main Authors: Reeves, Analise Z., Campbell, Patricia J., Sultana, Razvan, Malik, Seidu, Murray, Megan, Plikaytis, Bonnie B., Shinnick, Thomas M., Posey, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623337/
https://ncbi.nlm.nih.gov/pubmed/23380727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02191-12
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