Aminoglycoside Cross-Resistance in Mycobacterium tuberculosis Due to Mutations in the 5′ Untranslated Region of whiB7

Since the discovery of streptomycin's bactericidal activity against Mycobacterium tuberculosis, aminoglycosides have been utilized to treat tuberculosis (TB). Today, the aminoglycosides kanamycin and amikacin are used to treat multidrug-resistant (MDR) TB, and resistance to any of the second-li...

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Bibliografische gegevens
Hoofdauteurs: Reeves, Analise Z., Campbell, Patricia J., Sultana, Razvan, Malik, Seidu, Murray, Megan, Plikaytis, Bonnie B., Shinnick, Thomas M., Posey, James E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2013
Onderwerpen:
Mechanisms of Resistance
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623337/
https://ncbi.nlm.nih.gov/pubmed/23380727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02191-12
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