The Mycobacterial Transcriptional Regulator whiB7 Gene Links Redox Homeostasis and Intrinsic Antibiotic Resistance

Intrinsic drug resistance in Mycobacterium tuberculosis limits therapeutic options for treating tuberculosis. The mycobacterial transcriptional regulator whiB7 contributes to intrinsic resistance by activating its own expression and many drug resistance genes in response to antibiotics. To investiga...

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Detalhes bibliográficos
Main Authors: Burian, Ján, Ramón-García, Santiago, Sweet, Gaye, Gómez-Velasco, Anaximandro, Av-Gay, Yossef, Thompson, Charles J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249081/
https://ncbi.nlm.nih.gov/pubmed/22069311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.302588
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