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The chromatin remodeler CHD8 governs hematopoietic stem/progenitor survival by regulating ATM-mediated P53 protein stability

The Chd8 gene encodes a member of the chromodomain helicase DNA-binding (CHD) family of SNF2H-like adenosine triphosphate (ATP)-dependent chromatin remodeler, the mutations of which define a subtype of autism spectrum disorders. Increasing evidence from recent studies indicates that ATP-dependent ch...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Tu, Zhaowei, Wang, Chen, Davis, Ashley K., Hu, Mengwen, Zhao, Chuntao, Xin, Mei, Lu, Q. Richard, Zheng, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310427/
https://ncbi.nlm.nih.gov/pubmed/34292326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020009997
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