Chromatin remodeler CHD7 regulates the stem cell identity of human neural progenitors

Multiple congenital disorders often present complex phenotypes, but how the mutation of individual genetic factors can lead to multiple defects remains poorly understood. In the present study, we used human neuroepithelial (NE) cells and CHARGE patient-derived cells as an in vitro model system to id...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Chai, MuhChyi, Sanosaka, Tsukasa, Okuno, Hironobu, Zhou, Zhi, Koya, Ikuko, Banno, Satoe, Andoh-Noda, Tomoko, Tabata, Yoshikuni, Shimamura, Rieko, Hayashi, Tetsutaro, Ebisawa, Masashi, Sasagawa, Yohei, Nikaido, Itoshi, Okano, Hideyuki, Kohyama, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830929/
https://ncbi.nlm.nih.gov/pubmed/29440260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.301887.117
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