T-type Calcium Channels Determine the Vulnerability of Dopaminergic Neurons to Mitochondrial Stress in Familial Parkinson Disease

Parkinson disease (PD) is a progressive neurological disease caused by selective degeneration of dopaminergic (DA) neurons in the substantia nigra. Although most cases of PD are sporadic cases, familial PD provides a versatile research model for basic mechanistic insights into the pathogenesis of PD...

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Vydáno v:Stem Cell Reports
Hlavní autoři: Tabata, Yoshikuni, Imaizumi, Yoichi, Sugawara, Michiko, Andoh-Noda, Tomoko, Banno, Satoe, Chai, MuhChyi, Sone, Takefumi, Yamazaki, Kazuto, Ito, Masashi, Tsukahara, Kappei, Saya, Hideyuki, Hattori, Nobutaka, Kohyama, Jun, Okano, Hideyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234903/
https://ncbi.nlm.nih.gov/pubmed/30344006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.09.006
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