Chromatin remodeler CHD7 regulates the stem cell identity of human neural progenitors

Multiple congenital disorders often present complex phenotypes, but how the mutation of individual genetic factors can lead to multiple defects remains poorly understood. In the present study, we used human neuroepithelial (NE) cells and CHARGE patient-derived cells as an in vitro model system to id...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Chai, MuhChyi, Sanosaka, Tsukasa, Okuno, Hironobu, Zhou, Zhi, Koya, Ikuko, Banno, Satoe, Andoh-Noda, Tomoko, Tabata, Yoshikuni, Shimamura, Rieko, Hayashi, Tetsutaro, Ebisawa, Masashi, Sasagawa, Yohei, Nikaido, Itoshi, Okano, Hideyuki, Kohyama, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2018
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830929/
https://ncbi.nlm.nih.gov/pubmed/29440260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.301887.117
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi