Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8

Oligodendrocyte precursor cells (OPCs) constitute the main proliferative cells in the adult brain, and deregulation of OPC proliferation-differentiation balance results in either glioma formation or defective adaptive (re)myelination. OPC differentiation requires significant genetic reprogramming, i...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Marie, Corentine, Clavairoly, Adrien, Frah, Magali, Hmidan, Hatem, Yan, Jun, Zhao, Chuntao, Van Steenwinckel, Juliette, Daveau, Romain, Zalc, Bernard, Hassan, Bassem, Thomas, Jean-Léon, Gressens, Pierre, Ravassard, Philippe, Moszer, Ivan, Martin, Donna M., Lu, Q. Richard, Parras, Carlos
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2018
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PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126750/
https://ncbi.nlm.nih.gov/pubmed/30108144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802620115
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