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Targeting JAK/STAT Signaling Antagonizes Resistance to Oncolytic Reovirus Therapy Driven by Prior Infection with HTLV-1 in Models of T-Cell Lymphoma

Human T-cell leukemia virus type 1 (HTLV-1) is a retrovirus that infects at least 10 million people worldwide and is associated with the development of T-cell lymphoma (TCL). The treatment of TCL remains challenging and new treatment options are urgently needed. With the goal of developing a novel t...

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Publicado no:Viruses
Main Authors: Islam, Shariful, Espitia, Claudia M., Persky, Daniel O., Carew, Jennifer S., Nawrocki, Steffan T.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310324/
https://ncbi.nlm.nih.gov/pubmed/34372612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13071406
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