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Human Peptides α-Defensin-1 and -5 Inhibit Pertussis Toxin

Bordetella pertussis causes the severe childhood disease whooping cough, by releasing several toxins, including pertussis toxin (PT) as a major virulence factor. PT is an AB(5)-type toxin, and consists of the enzymatic A-subunit PTS1 and five B-subunits, which facilitate binding to cells and transpo...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Kling, Carolin, Pulliainen, Arto T., Barth, Holger, Ernst, Katharina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310310/
https://ncbi.nlm.nih.gov/pubmed/34357952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins13070480
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