Cysteine Mutations in the Ebolavirus Matrix Protein VP40 Promote Phosphatidylserine Binding by Increasing the Flexibility of a Lipid-Binding Loop

Ebolavirus (EBOV) is a negative-sense RNA virus that causes severe hemorrhagic fever in humans. The matrix protein VP40 facilitates viral budding by binding to lipids in the host cell plasma membrane and driving the formation of filamentous, pleomorphic virus particles. The C-terminal domain of VP40...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Viruses
Egile Nagusiak: Johnson, Kristen A., Bhattarai, Nisha, Budicini, Melissa R., LaBonia, Carolyn M., Baker, Sarah Catherine B., Gerstman, Bernard S., Chapagain, Prem P., Stahelin, Robert V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310056/
https://ncbi.nlm.nih.gov/pubmed/34372582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13071375
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