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Detection of lipid-induced structural changes of the Marburg virus matrix protein VP40 using hydrogen/deuterium exchange-mass spectrometry

Marburg virus (MARV) is a lipid-enveloped virus from the Filoviridae family containing a negative sense RNA genome. One of the seven MARV genes encodes the matrix protein VP40, which forms a matrix layer beneath the plasma membrane inner leaflet to facilitate budding from the host cell. MARV VP40 (m...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wijesinghe, Kaveesha J., Urata, Sarah, Bhattarai, Nisha, Kooijman, Edgar E., Gerstman, Bernard S., Chapagain, Prem P., Li, Sheng, Stahelin, Robert V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391744/
https://ncbi.nlm.nih.gov/pubmed/28167534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.758300
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